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doi: 10.1053/j.gastro.2013.11.044 47 CraigCMLiuLNguyenTPriceCBinghamCMcLaughlinTLet al

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74 In a comparative study in obese male mice of vertical sleeve gastrectomy (VSG), semaglutide treatment, and controls, both interventions improved glycemic control and reduced body weight, but VSG significantly decreased energy expenditure and induced notable bone loss, whereas semaglutide preserved BMD over six weeks

Larger portions can also feel heavier or less satisfying to someone whose appetite is already suppressed by a GLP-1