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2 Succinate supplementation or TMLHE inhibition decrease resistance to DNA damaging agents

Eur J Pharmacol (2017) 794:3744

Regeneron Pharmaceuticals Sector: Muscle-preserving antibody combinations and GLP-1 therapy for obesity HQ: Tarrytown, NY Year Founded: 1988 Origin Story: Founded in 1988 by Leonard Schleifer, MD, PhD, a neurologist and assistant professor at Cornell University Medical College on the premise that drug discovery could be industrialized through proprietary antibody-generation technology

Rodent studies have shown that treatment with liraglutide or once-weekly exenatide is associated with thyroid C-cell proliferation and the formation of thyroid C-cell tumors ( Therefore, the US Food and Drug Administration (FDA) prohibits these therapies for patients with an individual or family history of medullary thyroid carcinoma (MTC) or patients with multiple endocrine neoplasia syndrome type 2 (MEN2)

Exp Cell Res (2011) 317:2941

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