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Actinomycetes produce 0.1% of known microbial secondary metabolites, Bacillus produce 7.0% and other bacteria produce 12% 7

It is not approved by the FDA or EMA for human use, no Phase III human clinical trials have been published, and its legal status varies by jurisdiction

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OTA binds to plasma albumin and is metabolized into OTA before being eliminated through urine and feces [51]