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The reproductive process is known as amplexus and consists of a male grasping a females back and fertilizing the eggs externally

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Moreover, it was reported that supplementing the diet with the antioxidants N -acetylcysteine and vitamin E markedly increases tumor progression and reduces survival in mouse models of B-RAF- and K-RAS-induced lung cancer, by reduction of ROS, DNA damage, and p53 expression (Sayin et al., 2014)

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2.3.3 Molecular pathogenesis and disease mechanisms The development of ALS is driven by several overlapping biological mechanisms that together cause motor neuron degeneration