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3.3 Tirzepatide effects: cardiovascular, renal, hepatic, and other metabolic effects of tirzepatide Due to concerns that type 2 diabetes medications increased cardiovascular risk, the FDA issued guidance for pharmaceutical companies to perform cardiovascular outcomes trials for new diabetes medications

Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure

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The current fervor for GLP-1RAs in the capital markets as well as in the general public, especially in terms of weight reduction, is probably going to result in overuse, said Chun-Su Yuan, MD, PhD, the Cyrus Tang Professor of Anesthesia and Critical Care at the University of Chicago

Body composition substudies using imaging techniques confirmed that visceral adipose tissue decreased alongside total fat mass