Diese Komplexbildung unterscheidet es von typischen Peptiden ohne Metallkomplexation
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While not officially approved for weight loss, many patients experience modest weight reduction due to the loss of glucose (and calories) through urine
As Healio previously reported, obesity drugs such as the FDA-approved tirzepatide (Zepbound, Eli Lilly) and the investigational medication retatrutide (Eli Lilly) are agents that target and activate multiple receptors, with tirzepatide being a GLP-1/glucose-dependent insulinotropic polypeptide (GIP) dual agonist and retatrutide a GLP-1/GIP/glucagon triple agonist
The TRIUMPH-1 trial, which focuses on core obesity management, is expected to read out in mid-2026
Data availability The datasets analyzed during the current study are not publicly available as it is meant to be published as Meta data sharing may publicise long term aim of this research however, data can be available from the corresponding author on reasonable request