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C3G intervention in animals significantly downregulates the level of ROS in the pancreas of diabetic db/db mice, upregulates the activities of superoxide dismutase (SOD) and catalase (CAT), alleviates the islet OS induced by hyperglycemia in diabetic mice, and ameliorates T2DM (Ye X

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About the study The Phase 2 study (NCT06230523) was a 48-week, randomized, double-blind, placebo-controlled trial comparing the efficacy and safety of once-weekly eloralintide monotherapy with placebo in adults with obesity or overweight and at least one weight-related comorbidity and without type 2 diabetes

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