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DOI: Published online: February 14, 2024 1 Borthwick Diabetes Research Centre, Lister Hospital, Stevenage, UK 2 Diabetes Complications Research Centre, University College Dublin, Dublin, Ireland Corresponding author: Adie Viljoen

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Glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 are incretin hormones that regulate insulin secretion in response to nutrient intake, to facilitate glucose tolerance [81]

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Important safety considerations include vitamin K content if you take warfarin (consistent intake is important for stable anticoagulation), and timing of mineral-containing supplements if you take levothyroxine, tetracyclines, or quinolone antibiotics (separate by at least 4 hours for levothyroxine and 2 hours for antibiotics)