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For example, clinical data shows that semaglutide may reduce cardiovascular risk in persons with T2D and other cardiometabolic disorders

The patients diabetes was historically well controlled on oral hypoglycemic agents, but a recent flare of degenerative back pain required the use of injectable and oral steroids, resulting in elevated blood sugar levels and the need for additional medications

In the chart above, you can see that among people scoring in the top 1% of this BMI Polygenic Score (PGS) almost 70% had obesity

Instead, Amylin reduced its staff from 300 to 37

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