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Patients in the later period compared with the earlier period had more severe kidney dysfunction (stage 3: 52.1% vs

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November 1, 2017

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But these drugs caused weight loss, and research was showing improvements in other conditions including reduction in the risk of heart attacks and strokes

Only one of the trials included in the systematic review used the next-generation GLP-1 agonist semaglutide to treat obesity in adolescents aged 1218 years, and none used the combined GLP-1 and glucose-dependent insulinotropic peptide agonist, tirzepatide