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Both medications suppress appetite, both cause gastrointestinal side effects that can lead to dehydration, and both produce weight loss that stresses the musculoskeletal system

These trials showcased its superior efficacy in glycemic control and weight management

Frequently Asked Questions Can GLP-1 medications like Ozempic cause swelling in the legs

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Treatment intensification should be considered when HbA1c rises to 58 mmol/mol (7.5%) or higher on lifestyle interventions and metformin, though individualised targets may be appropriate