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Musumeci O, Barca E, Lamperti C, Servidei S, Comi GP, Moggio M, Mongini T, Siciliano G, Filosto M, Pegoraro E, Primiano G, Ronchi D, Vercelli L, Orsucci D, Bello L, Zeviani M, Mancuso M, Toscano A

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rare at research dosing intervals The nausea is the primary tolerability issue in research

Intracellular GSH/GSSG measurement The GSH and GSSG levels in whole liver tissues or cultured cells were measured using OxiSelect Total Glutathione (GSSG/GSH) Assay Kits in accordance with the manufacturers instructions (Cell Biolabs, San Diego, CA, USA)

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Highlights The incidence of epilepsy in children with mitochondrial disease is higher than in adults