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Jardiance can increase the risk of the following, which require immediate medical attention: Urinary tract infections, which can be severe Yeast infections of the genitals Ulcers of the lower limbs, which may require amputation in severe cases Fourniers Gangrene, a condition that can be life-threatening and can cause pain, redness, tenderness, or swelling around the genitals or anus, along with fever and fatigue Consult your healthcare provider for more information about what to watch for when taking Jardiance or Trulicity, as theyll be more familiar with your personal medical history and any other medications or supplements youre taking that may interact with Ttulicity and or Jardiance

However, anterior vaginal wall prolapse may be associated with frequency, urgency, incontinence, or obstructive urinary symptoms, and treatment of prolapse may be considered in select IC/BPS patients