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The company that performed this research, a pharmacy benefits manager, said this finding was surprising compared to past research showing a long-term rate of about 50%

Cancer Res 61 : 71307135

Considerations for Older Adults and Multiple Health Conditions Older adults with CKD often face multiple health challenges, making them more prone to drug interactions and side effects when starting GLP-1 therapy

Preclinical and clinical studies, in fact, demonstrate that glucagon receptor agonism in combination with GLP-1 receptor agonism reduces glucose levels and enables weight loss

Consequently, more comprehensive and in-depth investigations are necessary to ascertain whether immune cells truly express GLP-1R and to comprehend how GLP-1R signaling could directly influence the biology of immune cells

DOI: 10.1101/cshperspect.a029694