cjc-1295 ipamorelin mechanism of action gh igf-1 release + CJC-1295 No DAC Ipamorelin 10mg

2011, 3: 96ra77-10.1126/scitranslmed.3001318

Drugs@FDA, NDA 022505 (approved 10 Nov 2010)

Research Driven

In rodent and primate metabolic models, amylin analogue administration has been shown to attenuate glucagon-driven hepatic glucose output and reduce postprandial glycemic excursions, independently of insulin secretion (Verchere et al., Proceedings of the National Academy of Sciences, 1996

J.WangZ.ChenQ.GebaG

On the one hand, active platinum ions bind to the genomic DNA of tumor cells to form platinumDNA adducts, block DNA replication and transcription, and ultimately mediate tumor cell apoptosis/necrosis to exert anti-tumor effects