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A 48-week phase 2 retatrude trial with 338 overweight or obese non-diabetics reported dose-dependent weight reductions and improvements in waist circumference, blood pressure, glycated hemoglobin, fasting glucose and insulin, and most lipids except HDL

Front Med (Lausanne) 9:855141

NP (with delegated authority)

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Additionally, glutamine-derived aspartate plays a crucial role in hypoxic environments or environments with electron transport chain (ETC) impairment 28

Notably, Thompson himself acknowledges that the long-standing advice to eat less and exercise more has coincided with worsening health outcomes across all age groups