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Cokluk E, Sekeroglu MR, Aslan M, Balahoroglu R, Bilgili SG, Huyut Z

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However, more prospective studies are required to define the best dose and duration for riboflavin supplementation in these patients

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Brain Health Support Chlorogenic acid found in green coffee bean may support brain health by keeping neurodegenerative disorders at bay

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[1] [13] When B12 levels are borderline or clinical suspicion remains high despite normal B12, additional tests include: Holotranscobalamin (active B12) , which may be more sensitive in early or borderline deficiency Methylmalonic acid (MMA) and homocysteine levels, which become elevated in functional B12 deficiency (note that MMA is also elevated in renal impairment, and homocysteine rises in folate and B6 deficiency) Full blood count to identify macrocytic anaemia (elevated mean cell volume) Blood film examination may show hypersegmented neutrophils and megaloblastic changes Serum folate should be checked concurrently, as deficiencies often coexist Investigating the underlying cause is essential for appropriate management

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Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases

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