Click on the links below to view the notifications published by the Department of Health & Social Care, plus the guidance document from ABCD & PCDS: Medicine Supply Notification (MSN/2023/061) National Patient Safety Alert: Shortage of GLP-1 receptor agonists Guidance from ABCD & PCDS: GLP-1 RA National Shortage Tell a colleague Share this programme with your colleagues
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Melanosis, melanocytic hyperplasia, and primary malignant melanoma of the nasal cavity
unexpected signals noted (e.g., polycystic ovary) but not vaginal dryness as a labelled ADR
Novo Nordisk first developed semaglutide for type 2 diabetes (Ozempic, FDA-approved 2017) and later for chronic weight management (Wegovy, 2021)
Its concurrent engagement of GLP-1R, GIPR, and GCGR distinguishes it structurally and pharmacologically from both selective GLP-1R agonists such as semaglutide and dual GLP-1R/GIPR agonists such as tirzepatide