Biomedicines 10 , 2693 (2022)
Verdict: Clinically proven but still subject to some gut degradation
Nmeth and Boda measured a xanthine oxidase activity index and a GSSG/GSH ratio in infants and children with septic shock and showed that these indices were significantly correlated with each other, with severity of illness scores (PRISM), and were increased in patients in a proinflammatory state (26)
But pharmaceutical 5AR inhibitors come with baggagesexual side effects, mood changes, and a reputation that makes many men hesitant to use them
BPC-157 is created synthetically in labs
5-Amino-1MQ is studied for its proposed NNMT inhibition properties, with downstream research interest in NAD+ pathway and SIRT1 signalling modulation, while Methylene Blue is studied for distinct redox and electron-transfer properties relevant to mitochondrial pathway research