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The HPA axis mediates the body stress response, and dysregulation of this axis can amplify immune activation

Starting body composition plays a major role, with individuals carrying higher body fat percentages often experiencing more dramatic absolute changes, while leaner individuals may see slower but steady improvements in stubborn fat areas

Glutathione protects collagen and elastin fibers from oxidative damage, helping maintain skin structure and resilience

This protective mechanism is very important in organs of detoxification such as the liver and kidneys

These changes lead to the disease's clinical symptoms

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