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At steady state, body burden is approximately 1015 times the single-dose absorbed amount, bringing plasma concentrations into the therapeutic range despite extremely low and variable per-dose absorption
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Two-thirds of surveyed physiotherapists in Australia, New Zealand and Ireland are very confident in their diagnosis of GTPS (245/361, 67.9%), with the highest proportion of very confident physiotherapists in Australia (75.8%) 1
Retinal Disorders (e.g., NAION) While generally well tolerated, some individuals may experience mild and temporary side effects, such as: Flushing or facial warmth, headache or mild dizziness, nausea or upset stomach, temporary changes in blood pressure, and mild anxiety or emotional sensitivity (in rare cases with PT-141 or oxytocin)