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This procedure resulted in a pellet containing the cerebrovasculature and a floating parenchymal layer separated by a dextran interface

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CPB2, a key regulator of fibrinolysis, has previously been associated with thrombotic complications and disease severity in COVID-19 53,54,55

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Single-cell RT-PCR All neurons collected in retrograde tracing studies and used to assess calcium response and patch-clamp recording were picked up by the UnipicK + system (NeuroInDx) immediately after each measurement