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As a pentapeptide, it is subject to the standard limitations of peptide pharmacokinetics: it cannot be taken orally (destroyed by digestive enzymes), and it requires parenteral administration (subcutaneous injection being the most common route in research settings)

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GLP-1 is a hormone that regulates appetite, digestion and metabolic rhythm

Clinical trials have shown that Survodutide can significantly reduce liver fat and improve other markers of liver health, suggesting it may be more effective than traditional GLP-1 agonists in treating MASH2