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Larger randomized controlled trials are needed to confirm these findings and may help address concerns about indefinite therapy, lower healthcare costs, ease supply constraints, and broaden access to GLP-1 medications to improve public health, said the researchers.
Medication has to be within the realm of a lifestyle program
In several organ systems, at least part of the benefit appears to occur before major weight loss or independent of the number on the scale
Lancet Diabetes Endocrinol 6(8):605617 Tuttle KR, Lakshmanan MC, Rayner B, Busch RS, Zimmermann AG, Woodward DB et al (2018b) Dulaglutide versus insulin glargine in patients with type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7): a multicentre, open-label, randomised trial
These include improving sleep quality, managing mental stress, minimizing substance use, and nurturing positive social connections [173,174]
