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In addition to being involved in the transport of endogenous (e.g., neurotransmitters) and exogenous (e.g., drugs) substances [178], it also receives carnitine transport [179, 180]

Subsequently, the non-dopaminergic systems will be involved in the progression of the disease, causing some nonmotor symptoms, for instance, depression and cognitive decline [49,50,51]

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The central mechanism of action differentiates the compound from peripherally acting vasodilatory agents and has generated significant research interest in models of CNS-regulated physiological responses

Vitamin C and Selenium These nutrients act as "co-factors." Selenium is a mineral that helps the enzyme glutathione peroxidase function, while vitamin C helps "recharge" glutathione once it has spent its antioxidant power