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GLP-1R agonizts prevented the onset of ER stress and subsequent apoptosis in human umbilical vein endothelial cells when stimulated by high glucose 19

Cells were seeded in 24-well plates and transfected 24 h later using Lipofectamine 3000 with 100 ng of the reporter construct or an empty vector (GV308) as a negative control

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revealed that MTX treatment altered protein metabolism (Reference Boukhettala, Leblond and Claeyssens34)

4a) and 3 g kg 1 (Fig

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