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However, one study found that headaches occurred slightly more often in people taking tirzepatide than the placebo: 9.4% of people taking Zepbound or Mounjaro reported headache, compared to 7.5% taking a placebo
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Buckley ST, Bkdal TA, Vegge A, Maarbjerg SJ, Pyke C, Ahnfelt-Rnne J, Madsen KG, Schele SG, Alanentalo T, Kirk RK, Pedersen BL, Skyggebjerg RB, Benie AJ, Strauss HM, Wahlund PO, Bjerregaard S, Farkas E, Fekete C, Sndergaard FL, Borregaard J, Hartoft-Nielsen ML, Knudsen LB
doi: 10.1016/j.biomaterials.2025.123323 44 GaoW.LinW.TianM.FanS.EdwardsS.TranJ.et al
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