Clinicians might consider preferring GLP-1 receptor agonists over other diabetes treatments, such as insulin, for patients at high risk of obesity-associated cancers. Wang and colleagues conducted a retrospective cohort study of deidentified electronic health records on the TriNetX platform
Moreover, peptides were considered poor drug candidatesthey required injection, were expensive to manufacture, and were generally viewed as fragile molecules unsuitable for widespread therapeutic use
We then met to select six molecules that we deemed suitable for future human clinical trials in HS given the preclinical results already obtained in animals, particularly those that have a demonstrated effect on survival
R.WolfgeherD.et al (2014)
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Prevention and early detection are viewed as opportunities that could lead to substantial gains in PDAC-related outcomes