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The good news is that this symptom typically improves within 2-3 weeks as your body adapts, and several practical strategies can ease discomfort while your dose is being optimized

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Since semaglutide has a 7-day half-life, injecting on day 5 would compound the medication and potentially lead to higher-than-intended concentrations, increasing nausea, vomiting, and gastrointestinal side effects