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Os angioceratomas so o sinal cutneo mais comum, embora no seja especfico.59 Telangiectasias so relatadas como o segundo sintoma cutneo mais comum e so encontradas na face, lbios, mucosa oral e reas fotoexpostas.60 Com manifestaes desde a infncia, caracterizase por hipoidrose, parestesias, dor neuroptica acral, com alteraes renais, oculares, gastrintestinais, cardacas e predisposio a acidente vascular enceflico

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Perceptions of the targets SES We measured perceptions of the targets SES using the single-item MacArthur Scale of Subjective Social Status [47]

Anti-inflammatory Effects: It possesses anti-inflammatory properties that reduce redness, swelling, and skin irritation, which is beneficial for individuals with acne-prone or sensitive skin

2.1.2 Activation of innate immune pathways The mDAMPs discussed converge on specific innate immune pathways