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35,36 They can carry various cargo, including microRNAs (miRNAs), short noncoding RNA, proteins, DNA, messenger RNA (mRNA), nucleic acids and lipids

Overcoming these challenges will require advanced delivery platforms such as nanoparticles or hydrogels, personalized stratification tools such as lipidomic and ncRNA signatures, and rigorous pharmacokinetic validation in long-term OA models

Cell 14 , 661673 (2008)

But when the genotype is 677TT (homozygous), DNA over methylation is encountered [10]

Parks, T.D

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