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300 Alterations in p53-mediated processes, such as apoptosis, senescence, and mitochondrial respiration, are involved in the development of diabetic cardiomyopathy

SPRAWD Pickart L, Margolina A

Research in retinal pigment epithelial cells exposed to high glucose conditionsmodeling diabetic retinopathyshowed Epithalon restored impaired antioxidant gene expression and reduced intracellular ROS levels

Mol Cells 2008

If personnel take pyridostigmine in advance of exposure, soman will be prevented from binding to a significant percentage of available synaptic AChE because the AChE binding sites will be transiently occupied by pyridostigmine, and so irreversible soman aging (formation of a covalent bond) to the enzyme cannot take place

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