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Further work is needed to define the molecular mechanisms through which the clock coordinates CI abundance and function

Published on October 5th, 2025

doi: 10.1016/j.cell.2014.10.029 146 EganBZierathJR

Rational design of selective allosteric inhibitors of PHGDH and serine synthesis with anti-tumor activity

In human plasma, GHK concentrations decline from approximately 200 ng/mL at age 20 to roughly 80 ng/mL by age 60a decline coinciding with the noticeable decrease in regenerative capacity that every aging athlete experiences firsthand