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For skin specifically, this matters because the accumulation of senescent fibroblasts in aging dermis is one of the primary drivers of collagen loss

greater clinical integration requires clearer guideline recommendations and clinician awareness

Chu F-F, de Silva HR, Esworthy RS, Boteva KK, Walters CE, Roses A et al (1996) Polymorphism and chromosomal localization of the GI-form of human glutathione peroxidase (GPX2) on 14q24

Its also possible for some infections to cause SJS