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There are clear recommendations for who they work and for who they dont, especially when talking about weight loss in non-diabetics, said Dr Nikhil Tandon, interim director of AIIMS Delhi and former head of its endocrinology department

Weight comes back after stopping: in the STEP 1 extension, people regained about two-thirds of their lost weight within a year of stopping (Wilding and colleagues, Diabetes, Obesity and Metabolism , 2022)

Slowing gastric emptying, which extends the sensation of fullness and curbs overall calorie consumption

The gap between reliable vendors and unreliable ones is not small

Without this precision, the research data is meaningless

The lyophilized powder is stable for years at 20 C