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Routine liver function monitoring is not specifically required by FDA labels for patients on these medications unless other risk factors are present

This helps to reduce overall caloric intake, which is crucial for effective weight loss

Rapid weight loss without adequate protein leads to muscle loss, which slows metabolism and creates the "skinny fat" outcome where the scale looks good but body composition tells a disappointing story

Sensitivity analyses, including Fine-Gray competing risk models and a composite gynecologic cancer model, confirmed robustness of results (HR 0.69

Novo Nordisk recently reduced cash prices for Wegovy to $349/month for existing patients

Elevated natriuretic peptide levels have also been associated with increased risk of ischemic stroke and cognitive decline, as they indicate systemic vascular dysfunction and cerebral hypoperfusion