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Microglia and macrophages also directly mediate tissue injury through the release of pro-inflammatory cytokines (e.g., IL-1, IL-6, TNF-) and reactive mediators that contribute to oligodendrocyte and axonal damage (123)

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Mohamed MAE, Abdel-Rahman RF, Mahmoud SS, Khattab MM, Safar MM

The inflammatory response to neuronal injury induced by various stimuli culminates in the release of pro-inflammatory cytokines and cytotoxins, further exacerbating oxidative stress (137)

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Researchers study SS-31 for its potential interactions with cardiolipin and mitochondrial membrane function in preclinical models