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The complex pathophysiology and heterogeneity of the disease raises the speculation that combined treatment will be required for many patients

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Penicillamine, a copper chelator used in Wilson disease, requires dose adjustment in hepatic impairment precisely because liver function determines the rate at which mobilized copper can be processed and excreted [10]

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However, more research is needed to confirm its efficacy in humans

Xu, C., Sun, L., Ren, F., Huang, P., Tian, Z., Cui, J., Zhang, W., Wang, S., Zhang, K., He, L., Zhang, W., Zhang, C., Hao, Q., Zhang, Y., Li, M., & Li, W