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and iii) the tyrosine kinase receptor KIT/stem cell factor (SCF) pathway, all of which converge downstream to activate the master regulator-microphthalmia-associated transcription factor (MITF) (Fig
It's found in relatively high concentrations in several bodily tissues and plays critical roles in mitigating oxidative stress and inflammation, maintaining redox balance, enhancing metabolic detoxification processes, and regulating immune function 2
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Altered serotonergic signaling is considered a hallmark neurochemical feature of anxiety disorders (Yohn et al., 2017)
Free Radical Bio Med 40:21552165 Kubo A, Sano T, Saji H, Tanaka K, Kondo N, Tanaka K (1993) Primary structure and properties of glutathione-reductase from Arabidopsis thaliana
