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A rise in creatinine level up to 30% from baseline is an anticipated finding with drug initiation or dose modification and is due to the reduction in intraglomerular pressure

In contrast, patients with idiopathic vitiligo, although in the absence of occupational exposure, have very little chance to repair or reduce the lesion, regardless of the severity and the extension

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Warnings/Contraindications

[17] The drugs are approved to improve blood sugar control in adults aged 18 and older with type 2 diabetes