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Monthly follow-ups during dose titration assess: Laboratory monitoring every 3-6 months includes: Treatment duration varies individually, with many patients continuing long-term for weight maintenance

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The samples were taken before and 11 h after study drug administrationat the time of peak blood concentration of the liraglutide 11,12

A qualified healthcare provider should evaluate your medical history, current medications, and biomarker status before recommending supplementation

Abbreviations BAT: Brown adipose tissue CEX: C-terminal extension CNS: Central nervous system DIO: Diet-induced obese DPP-IV: Dipeptidylpeptidase-IV EMA: European Medicines Agency FDA: Food and Drug Administration GcgR: Glucagon receptor GIP: Glucose-dependent insulinotropic polypeptide GIPR: GIP receptor GLP-1: Glucagon-like peptide 1 GLP-1R: GLP-1 receptor OXM: Oxyntomodulin PEG: Polyethylene glycol STZ: Streptozotocin T 3 : Thyroid hormone References Obesity and overweight fact sheet

May 22, 2023