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It activates lysyl oxidase, an enzyme that crosslinks collagen fibers to create strong scar tissue

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so, when a scan shows less muscle mass after weight loss with glp-1s, it might be showing muscle getting leaner, i.e., losing the fat that surrounds the muscle, and not the muscle itself

An emerging mechanism of ferroptosis-like cell death points to cysteine loss as a key trigger, with one study demonstrating that erastin-induced cysteine deprivation triggered an alternative ferroptosis-like death pathway distinct from GPX4 inhibition, and that cysteine levels themselvesnot just glutathione levelswere the primary determinant of cellular fate

Treatment duration can vary based on each individuals goals, but many patients undergo treatments lasting several weeks or months