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J Strength Cond Res 24(5):12151222 Schwedhelm E, Maas R, Freese R, Jung D, Lukacs Z, Jambrecina A et al (2008) Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism

You will begin at a low dose and work your way up over several weeks to see the most benefit

For general daily supplementation, both forms are effective

Additionally, it slows down the rate at which food leaves the stomach, which helps in controlling appetite and reducing food intake

Participants randomized to retatrutide initiated treatment with 2 mg once weekly and increased the dose in a step-wise approach every four weeks until reaching the target dose of 9 mg (via steps at 2 mg, 4 mg and 6 mg) or 12 mg (via steps at 2 mg, 4 mg, 6 mg and 9 mg)