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It should be temporarily stopped during acute illness with dehydration, before iodinated-contrast imaging in some scenarios, and around major surgery: your team will tell you when

Study quality was not used as a reason for exclusion but was taken into account when interpreting the strength and reliability of the overall body of evidence

Transketolase activity was inhibited using 100 M oxythiamine (Sigma-Aldrich) for 48 h

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Tissue cells feel and respond to the stiffness of their substrate

[7] It works by increasing insulin release from the pancreas and decreases excessive glucagon release