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Weight gain (especially in the trunk and face), muscle weakness, thinning skin, easily bruising, elevated blood pressure, glucose intolerance, and mood swings are all typical signs of Cushings syndrome (27)

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All earlier GHRPs including GHRP-2 and GHRP-6 stimulated GH release but also produced dose-dependent elevations in ACTH and cortisol through activation of broader stress-response signalling pathways