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Glutathione (GSH) possesses significant antioxidant activity and plays an essential role in the health of humans

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Preclinical studies indicated that synthetic fragments corresponding to this domain could increase fat oxidation, affect adipocyte metabolism and reduce lipid deposition in models of obesity

190,191 The C-terminus of MDM2 is crucial for export of wild-type p53 from the nucleus to the cytoplasm, where it is degraded via E3 ubiquitin ligases

Complete cessation of lactation for a minimum of 2 to 4 weeks should precede treatment initiation