Olukorode et al., Recent Advances and Therapeutic Benefits of Glucagon-Like Peptide-1 (GLP-1) Agonists in the Management of Type 2 Diabetes and Associated Metabolic Disorders. [139]
Exposure to light and heat can cause chemical changes in the medication, which might make it less effective
An elevated heart rate may contribute to feelings of restlessness or anxiety, potentially disrupting sleep
METAOD clinical program (Phases I, II, IIb)
Note, however, that neither of these trials includes normal weight, non-diabetic patients with psoriasis and/or psoriatic arthritis
These reports align with the broader clinical literature on semaglutide tolerability