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2021 Dec 3;151(12):360616

CAMP/PKA pathway: Increases cAMP levels in osteoblasts, activates PKA, promotes the synthesis of bone matrix proteins (type I collagen, osteocalcin), and accelerates bone matrix mineralization

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13 Laboratory testing can also establish the presence of hyperandrogenism, and assessment of cardiometabolic risk, through both blood tests and medical history, is recommended