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But it became evident that another action of GLP1 is to suppress hunger and appetite by acting centrally on the brain, leading to these quite staggering weight-loss stories. Vis--vis the 15.2 per cent weight-loss figure from Novo Nordisks studies, that equated to around 15.9kg for most of the participants

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Most individuals start to experience positive changes within the first week, with optimal results developing over two to four weeks of consistent use

But it should sit inside a real plan: Treat the OSA now (PAP, oral appliance, positional therapy, surgerydepending on your case) Treat the weight driver long-term (nutrition, activity, behavioral support, medication when appropriate) Reassess (repeat sleep testing after meaningful weight change) And if your OSA is mainly anatomy-driven, we should focus on the airway strategy, not chase weight loss alone

Perform a patch test on a small area before reapplying and choose a serum with a lower concentration of vitamin C