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The primary objectives of this study are to evaluate the effect of elafibranor (120 mg/day) treatment in NASH patients (NAS 4) with stage 2/3 fibrosis compared to placebo on (1) histological improvement and (2) all-cause mortality and liver-related outcomes in patients with NASH and fibrosis

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In both in vitro and in vivo models of inflammatory osteoarthritis, ADSC-EVs are found to stimulate chondrogenesis while reducing cartilage degeneration and suppressing inflammation